WebThe decrease in the number of the receptors could result from the reduced synthesis of new receptors, also known as downregulation. Also, chronic exposure increases the degradation of preexisting receptors through endocytosis, also known as sequestration or internalization.

Downregulation - definition of downregulation by The Free …

WebNCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. WebDesensitization of G-protein coupled receptors following agonist occupancy is accompanied by two temporally distinguishable cellular trafficking phenomena of the receptors referred to as sequestration and down regulation. For the beta2-adrenergic receptor, sequestration occurs within minutes of agon … st xavier sector 81

What is an example of downregulation? - Studybuff

WebNov 28, 2015 · Receptor down regulation It is the response of cell for continuous exposure of ligand It is the reversible process Receptor down-regulation is the result of various cellular processes including receptor internalization, new synthesis, and recycling Most membrane receptors are internalized in the receptor mediated endocytosis For some … WebLipolysis / lɪˈpɒlɪsɪs / is the metabolic pathway through which lipid triglycerides are hydrolyzed into a glycerol and free fatty acids. It is used to mobilize stored energy during fasting or exercise, and usually occurs in … Webdownregulation. ( ˌdaʊnrɛɡjʊˈleɪʃən) n. (Medicine) a decrease in sensitivity, through overexposure, to a drug or other chemical caused by a reduction in the number or … st xavier university nova scotia