Sash1 gene
WebbID Human (hg19) Mouse (mm9) Expression Section Coordinates Bracketing Genes Coordinates Bracketing Genes ; mm456 : chr12:24,912,800-24,914,181 LINC00477-BCAT1 Webb1 mars 2024 · SASH1 gene is protein encoding genes that is a novel candidate of tumor suppressor gene. Moreover, SASH1 was encoded a scaffold protein which involved the toll-like receptor 4 (TLR4) signaling pathway for regulation of the cascade of cytokine production and endothelial cell migration in response to invading pathogens ( Dauphinee …
Sash1 gene
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WebbmRNA Protein Name; XM_020714609.1: XP_020570268.1: SAM and SH3 domain-containing protein 1 isoform X3: XM_011491627.3: XP_011489929.1: SAM and SH3 domain-containing protein 1 isof WebbABCB6 and SASH1 are recently reported pathogenic genes related to DUH, and the aim of this study was to identify the causative mutations in a Chinese family with DUH. Methods Sanger sequencing was performed to investigate the clinical manifestation and molecular genetic basis of these familial cases of DUH, bioinformatics tools and multiple sequence …
WebbView SASH1 mouse/human homology from Alliance Direct with: genes, location, sequences, associated human diseases. Home; Genes; Phenotypes; Human ... (Entrez Gene) 607955 SASH1 (Alliance of Genome Resources) Chr6 q24.3-q25.1: Chr6:148193440-148552049 (+) GRCh38.p7: dyschromatosis universalis hereditaria: O94885 (UniProt … Webb4 aug. 2024 · SASH1 was firstly identified as a potential tumor suppressor gene in breast cancer, which played a crucial role in tumorigenesis, development, invasion and metastasis ( Zeller et al., 2003; Lin et al., 2012 ). In addition, SASH1 was also involved in various complex signaling pathways as a pivotal regulator or mediator ( Dauphinee et al., 2013 ).
Webb10 juni 2024 · SASH1 (SAM and SH3 domain containing 1), a member of the SLY-family of signal adapter proteins, was originally identified as a candidate tumor suppressor gene in solid cancers [ 1 ]. Recently,... Webb1 sep. 2024 · Recently, SASH1 has been identified as a tumor suppressor gene. The purpose of this study was to investigate the role and regulatory mechanism of SASH1 in HA. RT-PCR and Western blot were used to detect the expressions of SASH1, TRAF6 and EZH2 in HA tissues and cell lines.
• Rimkus C, Martini M, Friederichs J, et al. (2007). "Prognostic significance of downregulated expression of the candidate tumour suppressor gene SASH1 in colon cancer". Br. J. Cancer. 95 (10): 1419–23. doi:10.1038/sj.bjc.6603452. PMC 2360597. PMID 17088907. • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Webb24 feb. 2024 · Circ-ITCH has been shown to reduce hepatocellular carcinoma cell growth through targeting miR-224-5p and overexpressing its target gene, MafF, which is widely downregulated in multiple cancers . Similarly, circ-ITCH was demonstrated to stimulate SASH1 levels by sponging miR-106a-5p to affect glioma cell proliferation and invasion . programs for coding htmlWebbThe SASH1 gene of human HTR-8/SVneo cells was overexpressed by transfection of pEZ-Lv206-SASH1. After that, the CCK-8 assay, EdU assay, transwell assay, and flow cytometry were used to examine the cell proliferation, migration, invasion, and apoptosis. Results. programs for child learning up to age 2Webb13 apr. 2024 · Target genes of miR-526b-5p were c-Myc and Foxp1. c-Myc positively regulated the expression of Foxp1 by binding to the Foxp1 promoter location -146/-135. Finally, miR-526b-5p impeded ... 6 genes (i.e., BMPER, NEDD4L, Foxp1, c-Myc, SASH1, and EMP1) were expressed as expected (Fig. S1B). Therefore, 6 targets of miR-526b-5p were ... kyneton race resultsWebbSASH1 small interfering RNA (siSASH1) was used to investigate its function. Hindlimb motor function was evaluated by the Basso-Bresnahan-Beattie (BBB) assay. The gene … programs for college gradsWebb30 nov. 2024 · Medizin, inklusive einem Forschungspraktikum im Klinikum r.d.I. (München) Forschungsgruppe "Molekulare Tumorbiologie" unter der Leitung von PD Dr. Klaus-Peter Janssen (Thema Expression des Tumorsuppressors SASH1 in Gene-trap Mäusen") Weniger anzeigen kyneton pizza and wine barWebb15 feb. 2024 · Abstract Dyschromatosis universalis hereditaria (DUH) is a pigmentary genodermatosis characterized by a mixture of hyperpigmented and hypopigmented macules distributed randomly over the body. Although Sterile Alpha motif- and SH3 domain-containing protein 1 (SASH1) and ATP-binding cassette subfamily B, member 6 … kyneton places to eatWebbSASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer Burgess JT et al Oncotarget 2016;7(45):72807-72818 … kyneton race club