WebMay 16, 2024 · This defect is commonly seen with nutraceutical products and may be expressed in many ways. For example, interaction of ingredients in the core, often in the presence of moisture derived from the coating process, can create dark spots that remain visible through the coating. WebAug 21, 2014 · The most common tablet defects are; weight variation, friability variation, hardness prob- lems, picking, sticking, capping, laminating, chipping, mottling, and double pressing or im- pressions. The top three are most common tablet defects are; Capping & Laminating , Sticking& Picking, and Hardness variation.
COMMON TABLET DEFECTS.pdf - Defect Name Definition …
WebThe edges of the tablets are worn away or damaged during the coating run. Spray Drying (logo filling) Dried coating material creates a rough, uneven surface on the tablet and/or fills the logo or breakline, making the logo unreadable. WebMay 16, 2024 · This is another mechanical defect that occurs as tablets tumble during the coating process. In addition to unsuitable punch design, core surface erosion can be facilitated by over-wetting (which causes the tablet surface to soften and hence become less resistant to attritional effects), presence of centrally placed logo, insufficient film ... biting baby solutions
Preventing Film Coating Problems by Design - PharmTech
WebAug 7, 2024 · Defects related to the tableting process: 1. Capping: It is partial or complete separation of the top or bottom of the tablet due to air-entrapment in the granular … WebNov 1, 2024 · The stored details are used for identifying defective tablets during manufacturing.Results: The characteristics such as color, shape, number of pills, area, and perimeter of the normal tablets... WebSticking and picking during tablet manufacture has received increasing interest recently, as it causes tablet defects, downtime in manufacturing, and yield losses. The capricious nature of the problem means that it can appear at any stage of the development cycle, even when it has been deemed as low risk by models, tests, and previous experience. biting autumn evening meaning